Spry Oral Insight™ Microbiome Test

How it works What it tests Request a kit

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Get to Know Your Oral Microbiome

You know your blood pressure. You probably know your cholesterol. Your mouth has its own complex ecosystem and now you can learn more about some of the microorganisms within it.

Oral Insight analyzes your saliva for 16 specific microorganisms associated with different aspects of oral health. Collect your sample, register your kit, and mail it to the laboratory. Your results should be available approximately 10 days after the laboratory receives your sample.

Collect my Sample

At-home collection · Lab processed

Spry Oral Insight microbiome test kit and sample collection materials

Takes about 5 minutes. Already collected your sample? Register your kit before you ship it.

Don't have a kit yet? Here's how to get one →

Step 1 · Collection

Collect Your Sample

The whole thing takes about five minutes. For the most consistent results, follow the collection instructions included with your kit.

Before you begin

For at least 30 minutes before you collect, don't eat, drink, chew gum, brush, floss, or use mouthwash. Wash your hands.

1 · PrepareAllow saliva to collect naturally. Do not cough up mucus. Do not swallow.

2 · ActivateIf instructed, shake the activation solution for 15–30 seconds. Do not swallow it.

3 · CollectSpit into the tube until saliva reaches the fill line. Bubbles don't count.

4 · Add preservativePour the preservative into the collection tube.

5 · SecureClose the tube tightly and make sure the cap is fully sealed.

6 · MixInvert gently 5–10 times. Do not shake.

7 · LabelWrite your full name and date of birth on the label and apply it securely.

8 · PackagePut the tube in the specimen bag, seal it, then place it in the prepaid mailer.

9 · Hold for registration Your sample is collected and packaged. Register your Kit ID before dropping the mailer in the mail.

Next: register your kit before you ship. Your sample can’t be processed without a registered Kit ID.

Step 2 · Registration

Register Your Kit Before You Ship It

Registration is what connects your sample to your results. Without registration, the laboratory cannot connect the sample with your information or results.

1

Find your Kit IDIt's printed on the registration card inside your box.

2

Enter your kit informationType in the Kit ID and follow the prompts.

3

Tell us about your oral healthA few questions about your routine, so your results come back with context instead of raw numbers.

4

Review and sign your consentPlain language, electronic signature, one click.

5

Confirm and shipYou'll get a confirmation on screen and by email. Then your sample is ready to mail.

Start Registration

Registration is handled by the accredited lab that processes your sample. Can't scan the QR code? Call Customer Care at 1-877-599-5327.

The registration card included with your kit.

Why the form asks

Why We're Asking for This

Fair question. Here's the honest answer.

The lab needs your name and date of birth to match your saliva sample to your results and send them back to the right person. Questions about your oral health history and daily routine provide helpful context. Your results can then be reviewed alongside your dental history and other clinical information.

Your consent form spells out exactly what the lab does with your sample and what happens to it afterward. Read it before you sign it. We'd rather you take the extra minute.

Step 3 · Results

What Happens After You Mail It

1

The lab receives your sample

Your saliva is processed at an accredited laboratory.

2

Your results arrive in about 10 days

You will receive an email when your results are ready. Log in at spryoralinsight.com to see which of the 16 targeted microorganisms were detected and their reported levels, presented in easy-to-understand language.

3

Review, plan, and follow up

Results provide an educational snapshot from the time your sample was collected. Review them with your dental professional, make an appropriate oral-care plan, and consider repeat testing to compare results over time.

Important: What These Results Mean

Oral Insight is an educational oral-wellness test, not a diagnostic test. Results do not determine whether you have cavities, periodontal disease, an oral infection, or any systemic health condition. Consult your dental professional for examination, diagnosis, and treatment recommendations.

Inside your oral microbiome

What the Test Looks For

Your mouth contains hundreds of species of microorganisms. Many are normal members of the oral microbiome and play a role in its complex ecosystem. Oral health can be affected when the microbial community changes or becomes imbalanced—a state researchers call dysbiosis.

Oral Insight analyzes 16 targeted microorganisms. Some have historically been grouped into microbial complexes based on patterns observed in dental plaque. The panel also includes Streptococcus mutans, Candida species, and Pseudomonas aeruginosa.

The Red Complex

Porphyromonas gingivalis, Tannerella forsythia, and Treponema denticola are commonly known as the red-complex bacteria. Research has strongly associated these organisms with periodontitis and more advanced signs of gum disease targeted. Their detection in saliva does not diagnose periodontal disease or determine its severity.

The rest of what we measure

Other organisms included in the panel have been associated with biofilm development and microbial patterns observed in periodontal disease. Their presence alone does not establish that periodontal disease is present. S. mutans are one of several bacteria associated with the development of cavities. Candida species can be present in healthy mouths, but higher reported levels may warrant discussion with a dental or healthcare professional, particularly when symptoms or relevant risk factors are present.

Brushing answers one question: “Do I have plaque?” This test answers a more useful one: “What's actually in there?”

A closer look

What the Test Looks For

What Is Streptococcus mutans?

Streptococcus mutans, often shortened to S. mutans, is one of several bacteria associated with the development of cavities. When these bacteria metabolize certain sugars and other fermentable carbohydrates, they produce acids that can contribute to mineral loss from tooth enamel.

Detecting S. mutans does not mean you have a cavity or that you will necessarily develop one. Many factors influence cavity risk, including diet, saliva flow, fluoride exposure, oral hygiene, health history, and existing dental conditions. Your results provide educational information that you can review with your dental professional. They are not a diagnosis.

Whole-body context

Your Mouth Is Connected to the Rest of Your Body

Periodontitis is a chronic inflammatory disease affecting the gums and structures supporting the teeth. Researchers continue to study how periodontal inflammation and the movement of oral bacteria or bacterial products into the bloodstream may relate to overall health.

Research has found associations between periodontal disease and several systemic conditions, including cardiovascular disease, diabetes, Alzheimer's disease, and respiratory disease. An association does not establish that periodontal disease causes these conditions. Researchers have detected genetic material from certain oral microorganisms in some human atherosclerotic plaque samples. This does not establish that the microorganisms were alive, originated in the mouth, or caused cardiovascular disease.

An association is not proof of cause. Detecting microbial genetic material in arterial plaque does not establish how it arrived there or what role, if any, it played in the disease process. The relationship between periodontal and cardiovascular health remains under active study. Diabetes and periodontal disease are also understood to have a bidirectional relationship, meaning each may affect the management or progression of the other.

To be clear about what this test does.

Oral Insight does not diagnose heart disease, diabetes, Alzheimer's, or any other systemic condition. The presence of a given bacterium does not mean you will develop any of them.

The test provides information about targeted microorganisms associated with different aspects of oral health. You can review these findings with your dental professional alongside your symptoms, history, examination, X-rays, and periodontal measurements.

The practical loop

Test. Understand. Discuss. Follow Up.

The value of a saliva test is what you do with it.

TEST

Get a baseline

After the laboratory processes your sample, you will receive an educational baseline showing which targeted microorganisms were detected and their reported levels.

UNDERSTAND

Review the findings

Review which targeted microorganisms were detected and their reported levels. Share the results with your dental professional so they can be considered alongside your dental history and clinical findings.

DISCUSS

Build your plan

Based on your overall oral health, not the saliva results alone, your dental professional may recommend changes to your daily oral-care routine, diet, preventive care, professional treatment, or follow-up schedule.

FOLLOW UP

Compare over time

Repeat testing may allow you to compare reported microbial levels over time. Changes should be interpreted cautiously and discussed with your dental professional.

Oral Insight provides an educational tool for learning about your oral microbiome and following selected microbial levels over time. It complements but does not replace a professional dental evaluation.

Daily oral-care habits

Where Spry Fits In

Spry has spent more than 20 years on one idea: that daily habits can support a healthier oral environment, and that xylitol is a useful tool for getting there.

Certain cavity-associated bacteria, including some strains of S. mutans, can take up xylitol but cannot ferment it into acids the way they ferment many sugars. Xylitol is a nonfermentable sweetener used in gums, mints, toothpaste, and rinses. Research has examined how regular xylitol exposure may affect acid production and cavity-associated bacteria and help support a healthier oral environment.

Your daily oral-care habits can help support a healthier oral environment between dental visits. Spry products provide options that can be incorporated into an oral-care routine based on your individual needs and the guidance of your dental professional.

See the Spry lineup →

Limited early release

Don't Have a Kit Yet?

Oral Insight is in a limited early release right now, so kits are going out in batches. Tell us a bit about yourself and we'll let you know when one is available for you.

First Name

Last Name

Email

Are you a dental professional?

Anything we should know about why you're interested? (optional)

We'll email you when kits open up. No newsletter blast, no reselling your information.

FAQ

Questions People Ask

Is this a diagnosis?

No. Oral Insight is an educational and wellness tool. It shows you which organisms are present in your saliva and at what levels. It doesn't diagnose, treat, cure, or prevent any disease, and it isn't a substitute for a dental exam. Bring your results to your dental professional.

How long until I get results?

About 10 days from when the lab receives your sample.

What if I already ate or drank something today?

Wait at least 30 minutes after eating, drinking anything other than water, chewing gum, brushing, flossing, or using mouthwash before collecting your sample.

Do I need to register before I mail it?

Yes. An unregistered sample can't be matched to you, which means it can't be processed.

What happens to my sample after the lab tests it?

Your consent form covers this in detail. Read it during registration before you sign.

Can I take the test more than once?

Yes. Each test provides a snapshot from the time your sample was collected. Repeat testing may help you and your dental professional compare reported microbial levels over time, but differences between results do not prove that a particular product or routine caused the change.

Who processes the test?

An accredited laboratory partner handles all sample processing and result reporting.

Ready when you are

Get to Know Your Oral Microbiome

Collect your sample, register your kit, and mail it to the laboratory. After processing, you will receive educational information about the 16 targeted microorganisms.

Register My Kit

Request a kit →

For educational and oral-wellness awareness purposes only. Results provide information about selected microorganisms and their reported levels and are not intended to diagnose, treat, cure, monitor, or prevent any disease or dental condition. Oral Insight is not a substitute for regular dental examinations or professional dental care. Consult a dental professional with questions about your results. Samples are processed by an accredited laboratory.

Xlear Inc. | Customer Care 1-877-599-5327 | sprysmile.com