This study’s findings support the effectiveness and safety of xylitol nasal spray as a preventative measure against recurrent acute otitis media (AOM), in children between the ages of 1 and 4 years.

Margulis I, Cohen-Kerem R, Stein N, Roitman A, Cohen-Vaizer M, Fridman E, Gordin A. Xylitol nasal spray for prevention of recurrent acute otitis media in children: a prospective two-center cohort study. International Journal of Pediatric Otorhinolaryngology. 2023;182:111818. doi:10.1016/j.ijporl.2023.111818. (x-mol.com)